Omaha Veterans Affairs Medical Center; Assistant Professor, Department of Psychiatry, University of Nebraska Medical Center, Omaha, NE. Due to its relative lack of drug interactions, modafinil is a good alternative for elderly patients, who often receive multiple medications. Apathy was assessed using the Apathy Evaluation Scale developed specifically to identify apathy and also to differentiate this from depression. DISCUSSION: Apathy, reasons to prescribe provigil a common behavioral problem, is often mistaken for depression; however, apathy differs from depression in symptomatology, clinical presentation, and treatment options. Deficits in the dopamine receptor system are involved in the etiology of apathy; modafinil's increased dopaminergic transmission is thought to help alleviate apathy. 2007 Jan 30; ABSTRACT OBJECTIVE: To present a case of successful treatment of apathy syndrome with modafinil. CASE SUMMARY: A 78-year-old man with dementia and provigil dementia patients depression was also experiencing apathy that did not respond provigil patient teaching to antidepressants including escitalopram, a selective serotonin-reuptake inhibitor provigil discussion forum (SSRI). Escitalopram was discontinued and modafinil, a novel vigilance-promoting agent pharmacologically distinct from stimulants, was used to successfully treat the apathy. Modafinil ( Provigil, Alertec, etc ) for the apathetic elderly Modafinil Therapy for cost nuvigil vs provigil Apathy in an Elderly Patient by Padala PR, Burke WJ, Bhatia SC. To the best of our knowledge, as of January 22, 2007, this is the buy provigil cheap first report of modafinil treatment of apathy syndrome.